Substitution at R3 with a halogen or alkoxy group (74f–74i) triggered a slight rise in mobile potency Using the halide analogs (74g–h) displaying highest the potency in the group. Further more optimization brought about the discovery of 74i–j, with 74k as one of the most active compound in the sequence https://titusumbpe.goabroadblog.com/30759689/the-indazole-nmr-diaries