Esophageal Ailments together with noncardiac chest ache, swallowing Diseases, and regurgitation/rumination syndromes are frequent in clinical observe. Virtually all gastroenterologists and doctors handling these Diseases present empiric and symptomatic cure without the need of an evaluation or idea of the cause of the indicators. In an assessment With this challenge https://www.directivepublications.org/journal-of-gastroenterology-hepatology-and-endoscopy-research/