Metabolic alterations connected with T2D are very well characterised by epidemiological and research based reports. The pathogenesis and progression of T2D is ascribed to four mechanisms; increased Highly developed glycation end merchandise (AGE) development, increased polyol pathway flux, activation of protein kinase C (PKC) isoforms, and greater hexosamine pathway flux[seven]. https://www.directivepublications.org/journal-of-diabetology-research/